Patched (Ptc) is a conserved 12-pass transmembrane protein receptor that plays an obligate negative regulatory role in the Hedgehog signaling pathway in insects and vertebrates. Patched is an essential gene in embryogenesis for proper segmentation in the fly embryo, mutations in which may be embryonic lethal. Patched functions as the receptor for the Hedgehog protein and controls its spatial distribution, in part via endocytosis of bound Hedgehog protein, which is then targeted for lysosomal degradation.
Team mate
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Somebody on the same team that, no matter what, wont quit on you, will always defend you in front of non-team members and is there for the team.
Team mate meaning & definition 1 of Team mate.
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A person who is on the same team, Someone who wont RAT you out to coachs or capt.s, because you want to have the best team possible, Someone who doesnt always think about themselves when it comes to playing time, someone who no matter what, even if they have to PRETEND, will talk/ get along with a fellow team mate.
Team mate meaning & definition 2 of Team mate.
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a player on the same team
Team mate meaning & definition 3 of Team mate.
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