Patched (Ptc) is a conserved 12-pass transmembrane protein receptor that plays an obligate negative regulatory role in the Hedgehog signaling pathway in insects and vertebrates. Patched is an essential gene in embryogenesis for proper segmentation in the fly embryo, mutations in which may be embryonic lethal. Patched functions as the receptor for the Hedgehog protein and controls its spatial distribution, in part via endocytosis of bound Hedgehog protein, which is then targeted for lysosomal degradation.
Twenty
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Trucker term referring to location. Dervide from the Association of Public Safety Communication Officials ten-code, 10-20, meaning specify location/my location is ___
Twenty meaning & definition 1 of Twenty.
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The number equivalent to the product of two and ten; ten less than thirty; 20.
Twenty meaning & definition 2 of Twenty.
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twenty dollars worth of marijuana
Twenty meaning & definition 3 of Twenty.
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the typical form crack rocks are sold in.
Twenty meaning & definition 4 of Twenty.
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Point of view; perspective; attitude.
Twenty meaning & definition 5 of Twenty.
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