Patched (Ptc) is a conserved 12-pass transmembrane protein receptor that plays an obligate negative regulatory role in the Hedgehog signaling pathway in insects and vertebrates. Patched is an essential gene in embryogenesis for proper segmentation in the fly embryo, mutations in which may be embryonic lethal. Patched functions as the receptor for the Hedgehog protein and controls its spatial distribution, in part via endocytosis of bound Hedgehog protein, which is then targeted for lysosomal degradation.
Murk
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To physically beat someone so severely, they end up dying from their injuries. To beat the living shit outta someone. To seriously whoop somebodys ass.
Murk meaning & definition 1 of Murk.
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To kill; murder.
Murk meaning & definition 2 of Murk.
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to kill. beat the shit outta somone
Murk meaning & definition 3 of Murk.
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to win, beat or kill someone or something
Murk meaning & definition 4 of Murk.
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to murder
Murk meaning & definition 5 of Murk.
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to eliminate somethin badly, could be beating somebody up badly, finished some food in its entirety, and/or murder someone or somethin.
Murk meaning & definition 6 of Murk.
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Actually spelt Merc but these idiots below me dont seem to realise that. Short for Mercenary it means to destroy or to beat mercilessly
Murk meaning & definition 7 of Murk.
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A common misspelling of [merc], which means to beat up or kill someone. Used mainly in hip-hop and [gang] culture. Derived from mercenary, a soldier for hire.
Murk meaning & definition 8 of Murk.
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darkness or thick cloud, preventing you from seeing clearly:
Murk meaning & definition 9 of Murk.
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