A striped racer, also known as the California whipsnake, is a species of non-venomous snake native to the coast and foothills of California. It is a long, slender, and fast-moving snake, identified by its distinctive stripes running down the length of its body. They primarily feed on lizards and small rodents. The scientific name for this species is Masticophis lateralis.
Approach to the patient with suspected immunodeficiency
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Immunodeficiency typically manifests as recurrent infections. However, recurrent infections are more likely to have causes other than immunodeficiency (eg, inadequate treatment, resistant organisms, other disorders that predispose to infection). Both clinical and laboratory findings are needed for diagnosis.
(See also Overview of Immunodeficiency Disorders.)
Immunodeficiency can bePrimary: Genetically determined, typically manifesting during infancy or childhood
Secondary: AcquiredThere are many causes of secondary immunodeficiency, but most immunodeficiencies result from one or more of the following:
Systemic disorders (eg, diabetes, undernutrition, HIV infection)
Immunosuppressive treatments (eg, cytotoxic chemotherapy, bone marrow ablation before transplantation, radiation therapy)
Prolonged serious illness (particularly in critically ill, older, and/or hospitalized patients)Primary immunodeficiencies are classified by the main component of the immune system that is deficient, absent, or defective:
Humoral immunity
Cellular immunity
Combined humoral and cellular immunity
Phagocytic cells
Complement proteins
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