Patched (Ptc) is a conserved 12-pass transmembrane protein receptor that plays an obligate negative regulatory role in the Hedgehog signaling pathway in insects and vertebrates. Patched is an essential gene in embryogenesis for proper segmentation in the fly embryo, mutations in which may be embryonic lethal. Patched functions as the receptor for the Hedgehog protein and controls its spatial distribution, in part via endocytosis of bound Hedgehog protein, which is then targeted for lysosomal degradation.
Faller
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A part which acts by falling, as a stamp in a fulling mill, orthe device in a spinning machine to arrest motion when a threadbreaks.
Faller meaning & definition 1 of Faller.
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a person that falls in love with multiple people in a short amount of time but doesnt feel anything at all during the so called relationships
Faller meaning & definition 2 of Faller.
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someone who does something crazy and insanly stupid
Faller meaning & definition 3 of Faller.
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Any person who has achieved greatness in any extreme sport. One who has fallen a great number of times in the pursuit of greatness in an extreme sport. A fearless person. Someone who has gained wealth from their extreme sport.
Faller meaning & definition 4 of Faller.
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Is a person usually from Minnesota. They love to ride through corn with their trucks and kill random animals that no one has ever heard in random ways. They are often annoyed by German or Spanish phrases, and are known to wear emo attire. They also are known to sit at the back desk in S-15.
Faller meaning & definition 5 of Faller.