Patched (Ptc) is a conserved 12-pass transmembrane protein receptor that plays an obligate negative regulatory role in the Hedgehog signaling pathway in insects and vertebrates. Patched is an essential gene in embryogenesis for proper segmentation in the fly embryo, mutations in which may be embryonic lethal. Patched functions as the receptor for the Hedgehog protein and controls its spatial distribution, in part via endocytosis of bound Hedgehog protein, which is then targeted for lysosomal degradation.
Neutralized
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The rare circumstances in which a person is ultra hot and at the same time ultra cool. The word was created as a descriptive word for the two most neutralized people ever: Katie Hott and Gabe Greenberg
Neutralized meaning & definition 1 of Neutralized.
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past simple and past participle of neutralize
Neutralized meaning & definition 2 of Neutralized.
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