Patched (Ptc) is a conserved 12-pass transmembrane protein receptor that plays an obligate negative regulatory role in the Hedgehog signaling pathway in insects and vertebrates. Patched is an essential gene in embryogenesis for proper segmentation in the fly embryo, mutations in which may be embryonic lethal. Patched functions as the receptor for the Hedgehog protein and controls its spatial distribution, in part via endocytosis of bound Hedgehog protein, which is then targeted for lysosomal degradation.
Reface
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(v) To copy and repost a friends status on facebook.
Reface meaning & definition 1 of Reface.
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To add someone back to your Facebook friend list.
Reface meaning & definition 2 of Reface.
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(v) To re-establish a relationship on Facebook after removing it.
See [deface]Reface meaning & definition 3 of Reface.
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Put a new facing on (a building)
Reface meaning & definition 4 of Reface.
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