Patched (Ptc) is a conserved 12-pass transmembrane protein receptor that plays an obligate negative regulatory role in the Hedgehog signaling pathway in insects and vertebrates. Patched is an essential gene in embryogenesis for proper segmentation in the fly embryo, mutations in which may be embryonic lethal. Patched functions as the receptor for the Hedgehog protein and controls its spatial distribution, in part via endocytosis of bound Hedgehog protein, which is then targeted for lysosomal degradation.
Footage
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A piece of recent video or film.
Footage meaning & definition 1 of Footage.
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A noun describing shoes (or any other footwear), often used when bragging about new shoes.
Footage meaning & definition 2 of Footage.
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noun describing marijuana or any other mind altering, concsious elevating drug that produces enhanced sensory reception. most commonly used in the phrase sport that footage
Footage meaning & definition 3 of Footage.
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