Patched (Ptc) is a conserved 12-pass transmembrane protein receptor that plays an obligate negative regulatory role in the Hedgehog signaling pathway in insects and vertebrates. Patched is an essential gene in embryogenesis for proper segmentation in the fly embryo, mutations in which may be embryonic lethal. Patched functions as the receptor for the Hedgehog protein and controls its spatial distribution, in part via endocytosis of bound Hedgehog protein, which is then targeted for lysosomal degradation.
Communitarian
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a person or political party completely void of thought or reason. One void of the ability to think, who enjoys having their rights taken away.
Communitarian meaning & definition 1 of Communitarian.
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A late 20th Century Political movement that combines the major features of Marxist Communism and Facism.
Communitarian meaning & definition 2 of Communitarian.
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