Patched (Ptc) is a conserved 12-pass transmembrane protein receptor that plays an obligate negative regulatory role in the Hedgehog signaling pathway in insects and vertebrates. Patched is an essential gene in embryogenesis for proper segmentation in the fly embryo, mutations in which may be embryonic lethal. Patched functions as the receptor for the Hedgehog protein and controls its spatial distribution, in part via endocytosis of bound Hedgehog protein, which is then targeted for lysosomal degradation.
Fly catcher
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Angry snatch.
See: [alcove], [bat cave], [bear trap], [bearded clam], [bearded taco], [beaver], [bermuda triangle], [box], [bucket seat], [cake], [chuff box], [cockpit], [cooch], [coochie], [coochie-pop], [coose], [cooter], [cooze], [crack], [crawl space], [cum depository], [cum dumpster], [cuntcake], [cunt], [cunny], [donut], [dripping delta], [felted mound], [fillet-o-fish], [finger hut], [fish], [fish taco], [front bum], [fuckhole], [garage], [gash], [gates of Heaven], [golden doorway], [Grand Canyon], [growler], [hair pie], [hatchet wound], [heavens door], [hole], [honey cave], [honey pot], [hot box], [jaws of Hell], [lobster pot], [loins], [loose meat sandwich], [lotus], [love box], [love canal], [lower lips], [meat wallet], [muff], [nooch], [nook], [nookie], [peach], [pearly panty gates], [pocket], [poon], [poontang], [purse], [pussy], [quiff], [quim], [rat trap], [scratch], [sheath], [slash], [slit], [snapper], [snatch], [space], [split], [stench trench], [tampon socket], [temple], [thingy], [tool shed], [tuna], [tunnel], [twat], [undercut], [vagina], [vertical smile], [wishing well], [whisker box], [womb], [x], [yoni]
Fly catcher meaning & definition 1 of Fly catcher.
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A person who ambles around in a permanently gormless and confused state.
Fly catcher meaning & definition 2 of Fly catcher.
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A gormless, moronic person who looks like they struggle with simple tasks and cant seem to close their mouth at all as their teeth seem to be too large for their mouth.
Fly catcher meaning & definition 3 of Fly catcher.
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another term for moron. they breath mainly through their mouths, and can become confused when trying to do more than one thing at a time. this includes talking while breathing.
Fly catcher meaning & definition 4 of Fly catcher.