Patched (Ptc) is a conserved 12-pass transmembrane protein receptor that plays an obligate negative regulatory role in the Hedgehog signaling pathway in insects and vertebrates. Patched is an essential gene in embryogenesis for proper segmentation in the fly embryo, mutations in which may be embryonic lethal. Patched functions as the receptor for the Hedgehog protein and controls its spatial distribution, in part via endocytosis of bound Hedgehog protein, which is then targeted for lysosomal degradation.
Pickle
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A solution of salt and water, in which fish, meat, etc.,
may be preserved or corned; brine.
Pickle meaning & definition 1 of Pickle.
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A relish consisting of vegetables or fruit preserved in vinegar or brine.
Pickle meaning & definition 2 of Pickle.
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Create superhuman sales and customer success teams. A software product by Pickle
Pickle meaning & definition 3 of Pickle.
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a vegetable or fruit that has been preserved in vinegar or in salty water, especially a cucumber that has been preserved in this way:
Pickle meaning & definition 4 of Pickle.
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Speak your customers love language by listening deeper with conversation intelligence. A software product by Pickle
Pickle meaning & definition 5 of Pickle.
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