Patched (Ptc) is a conserved 12-pass transmembrane protein receptor that plays an obligate negative regulatory role in the Hedgehog signaling pathway in insects and vertebrates. Patched is an essential gene in embryogenesis for proper segmentation in the fly embryo, mutations in which may be embryonic lethal. Patched functions as the receptor for the Hedgehog protein and controls its spatial distribution, in part via endocytosis of bound Hedgehog protein, which is then targeted for lysosomal degradation.
Posers
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A poser is someone who tries to fit into a profile they aren't. People who try to give off the impression that they are one thing when they are really another.
Also, a poser can be one who says they can do something that they can't.
Or more commonly, a poser is someone who, when doing something successfully, takes more than enough credit for it.
Posers meaning & definition 1 of Posers.
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a problem or question that is difficult to solve or answer:
Posers meaning & definition 2 of Posers.
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