Patched (Ptc) is a conserved 12-pass transmembrane protein receptor that plays an obligate negative regulatory role in the Hedgehog signaling pathway in insects and vertebrates. Patched is an essential gene in embryogenesis for proper segmentation in the fly embryo, mutations in which may be embryonic lethal. Patched functions as the receptor for the Hedgehog protein and controls its spatial distribution, in part via endocytosis of bound Hedgehog protein, which is then targeted for lysosomal degradation.
Speculation
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An unidentified substance, resembling jizz, that appears somewhere it is not normally found.
Speculation meaning & definition 1 of Speculation.
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The forming of a theory or conjecture without firm evidence.
Speculation meaning & definition 2 of Speculation.
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When you make [a spec] out of you, and [some guy] named [lation].
Speculation meaning & definition 3 of Speculation.
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See turnover buying.
Speculation meaning & definition 4 of Speculation.
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the activity of guessing possible answers to a question without having enough information to be certain:
Speculation meaning & definition 5 of Speculation.
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