Patched (Ptc) is a conserved 12-pass transmembrane protein receptor that plays an obligate negative regulatory role in the Hedgehog signaling pathway in insects and vertebrates. Patched is an essential gene in embryogenesis for proper segmentation in the fly embryo, mutations in which may be embryonic lethal. Patched functions as the receptor for the Hedgehog protein and controls its spatial distribution, in part via endocytosis of bound Hedgehog protein, which is then targeted for lysosomal degradation.
Equator
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When you are fucking a girl and when you are about to cum, pull out, tell the girl to spin like a top, and you leave a nice trail around her waist. Experts can attempt the prime meridian or the tropic of breast cancer.
Equator meaning & definition 1 of Equator.
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The 0 degree line of [latitude] on a [map] or [globe]
Equator meaning & definition 2 of Equator.
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A line notionally drawn on the earth equidistant from the poles, dividing the earth into northern and southern hemispheres and constituting the parallel of latitude 0°.
Equator meaning & definition 3 of Equator.
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The [incorrect spelling] of [Ecuador]
Equator meaning & definition 4 of Equator.
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When a [Tan Line] on a [pen15] seperates both halves of the [Penor]. For example one half is tan the other is Albino white.
Equator meaning & definition 5 of Equator.
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Real-time collaboration, massive data library and custom title blocks. Make professional maps in minutes without years of training. A software product by Equator
Equator meaning & definition 6 of Equator.
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an imaginary line drawn around the middle of the earth an equal distance from the North Pole and the South Pole:
Equator meaning & definition 7 of Equator.