Patched (Ptc) is a conserved 12-pass transmembrane protein receptor that plays an obligate negative regulatory role in the Hedgehog signaling pathway in insects and vertebrates. Patched is an essential gene in embryogenesis for proper segmentation in the fly embryo, mutations in which may be embryonic lethal. Patched functions as the receptor for the Hedgehog protein and controls its spatial distribution, in part via endocytosis of bound Hedgehog protein, which is then targeted for lysosomal degradation.
Hammer
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Another word for [cock], [dick], or [penis].
Hammer meaning & definition 1 of Hammer.
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Gun, 9mm (used in New York City)
Hammer meaning & definition 2 of Hammer.
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Simply put, an attractive girl can be referred to as a hammer. If the aforementioned female is unbelieveably attractive, she can be called a jackhammer or sledgehammer, accordingly. A place where several hammers coexist can be refered to as Hammer City, or Hammerville, USA.
Hammer meaning & definition 3 of Hammer.
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Noun; A present tense word uncommonly used to describe the act of binge drinking. More commonly used as Hammered
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Noun; A word shouted to call upon Mjolnir, Thors hammer.
Used during times of distress and discomfort.
Subsequently, if shouted by a person who is righteous, a hammer will fly towards your open hand allowing you to lay the smack down and smite everything around you.
Hammer meaning & definition 4 of Hammer.
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A tool generally used in construction.
Hammer meaning & definition 5 of Hammer.
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Hammer in Field Events - Hammer. The hammer event is decided within six trials. The hammer is a round ball and chain made of metal and is one of the heavier throwing events.
Hammer meaning & definition 6 of Hammer.