Patched (Ptc) is a conserved 12-pass transmembrane protein receptor that plays an obligate negative regulatory role in the Hedgehog signaling pathway in insects and vertebrates. Patched is an essential gene in embryogenesis for proper segmentation in the fly embryo, mutations in which may be embryonic lethal. Patched functions as the receptor for the Hedgehog protein and controls its spatial distribution, in part via endocytosis of bound Hedgehog protein, which is then targeted for lysosomal degradation.
Philanthropy
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Love to mankind; benevolence toward the whole human family;universal good will; desire and readiness to do good to all men; --opposed to misanthropy. Jer. Taylor.
Philanthropy meaning & definition 1 of Philanthropy.
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Philanthropy meaning & definition 2 of Philanthropy.
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From the ancient Greek Phil
Philanthropy meaning & definition 3 of Philanthropy.
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The act of tying a burlap cord around one's sack to prolong the act of sex - especially when practicing the european act of a-nal.
Philanthropy meaning & definition 4 of Philanthropy.
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When rich white people donate to poor black kids because most likely they were accidents.
Philanthropy meaning & definition 5 of Philanthropy.
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A LAME STYLE OF DOGGING THE PRESIDENT OF THE UNITED STATES.
A style of cut downs used mostly by left wing cross dressers.Philanthropy meaning & definition 6 of Philanthropy.
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