These tumors arise from cells in the pancreas that produce vasoactive intestinal peptide.
The main symptom is watery diarrhea.
Diagnosis includes blood and imaging tests.
Treatment is replacement of fluids and electrolytes and surgery.

Vipomas are a type of pancreatic endocrine tumor. About 50 to 75% of these tumors are cancerous (malignant). In about 6% of people, vipoma occurs as part of a disorder called multiple endocrine neoplasia.