Patched (Ptc) is a conserved 12-pass transmembrane protein receptor that plays an obligate negative regulatory role in the Hedgehog signaling pathway in insects and vertebrates. Patched is an essential gene in embryogenesis for proper segmentation in the fly embryo, mutations in which may be embryonic lethal. Patched functions as the receptor for the Hedgehog protein and controls its spatial distribution, in part via endocytosis of bound Hedgehog protein, which is then targeted for lysosomal degradation.
Lovelock
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A long lock of hair hanging prominently by itself; an earlock;-- worn by men of fashion in the reigns of Elizabeth and James I.Burton.A long lovelock and long hair he wore. Sir W. Scott.
Lovelock meaning & definition 1 of Lovelock.
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sprung ; the act of being in love with someone so much that you wouldn't cheat on them ; faithfulness.
Lovelock meaning & definition 2 of Lovelock.
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Someone who excells in the art of Lovelocking paperwork, basically constantly looses important paperwork/important objects, espescially just before they are needed.
Lovelock meaning & definition 3 of Lovelock.
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a chubby brown haired school kid who dyes there hair blonde. Is also incredibly camp
Lovelock meaning & definition 4 of Lovelock.
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The act of putting your partner in a chock hold during doggy style or when they are face down.
Lovelock meaning & definition 5 of Lovelock.
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A padlock attached to a bridge by a couple as a symbol of their commitment to each other.
Lovelock meaning & definition 6 of Lovelock.
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