Patched (Ptc) is a conserved 12-pass transmembrane protein receptor that plays an obligate negative regulatory role in the Hedgehog signaling pathway in insects and vertebrates. Patched is an essential gene in embryogenesis for proper segmentation in the fly embryo, mutations in which may be embryonic lethal. Patched functions as the receptor for the Hedgehog protein and controls its spatial distribution, in part via endocytosis of bound Hedgehog protein, which is then targeted for lysosomal degradation.
Writing
-
a kind of love that thats annoying as hell and makes you want to pull your hair out. It keeps you up and night, and it makes you think about the world entirely differently. Its a passion that is unlike any other. It overides everything in your life.
Writing meaning & definition 1 of Writing.
-
The activity or skill of writing.
Writing meaning & definition 2 of Writing.
Similar Words