Patched (Ptc) is a conserved 12-pass transmembrane protein receptor that plays an obligate negative regulatory role in the Hedgehog signaling pathway in insects and vertebrates. Patched is an essential gene in embryogenesis for proper segmentation in the fly embryo, mutations in which may be embryonic lethal. Patched functions as the receptor for the Hedgehog protein and controls its spatial distribution, in part via endocytosis of bound Hedgehog protein, which is then targeted for lysosomal degradation.
RISC
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Stands for Reduced Instruction Set Computing,and is pronounced risk. It is arguably the fastest and most effiecient microprocessor technology available today. The RISC architechture is an improvement upon the CISC (Complex Instruction Set Computing) architecture used in the original Intel Pentium chips. In 1974, John Cocke of IBM Research was working on making a faster version of the CISC chip and came up with a design that significantly reduced the number of instructions need for performing computations. The new design was not only faster than the CISC architecture, but the chips were also smaller and less expensive to manufacture. Motorolas PowerPC chips (such as the G4 in Power Macs) are the most widely used RISC-based chips. Intel has slowly been integrating RISC technology into its chips, but they still are mostly CISC-based.
RISC meaning & definition 1 of RISC.