Patched (Ptc) is a conserved 12-pass transmembrane protein receptor that plays an obligate negative regulatory role in the Hedgehog signaling pathway in insects and vertebrates. Patched is an essential gene in embryogenesis for proper segmentation in the fly embryo, mutations in which may be embryonic lethal. Patched functions as the receptor for the Hedgehog protein and controls its spatial distribution, in part via endocytosis of bound Hedgehog protein, which is then targeted for lysosomal degradation.
Pally
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A common character in World of Warcraft with special healing talents. An abbreviation of Paladin.
Pally meaning & definition 1 of Pally.
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A friend of the late, great Dean Martin.
Pally meaning & definition 2 of Pally.
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In reference to someone who has done you wrong or just some idiot.
Dudes from the east coast and 1940s Los Angeles commonly use this reference.
Mostly used in second person.Pally meaning & definition 3 of Pally.
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Short form of paladin, a character class in Diablo 2. Rather appropriate because the paladins Auras can help nearby friendly characters.
Pally meaning & definition 4 of Pally.
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Having a close, friendly relationship.
Pally meaning & definition 5 of Pally.
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