Patched (Ptc) is a conserved 12-pass transmembrane protein receptor that plays an obligate negative regulatory role in the Hedgehog signaling pathway in insects and vertebrates. Patched is an essential gene in embryogenesis for proper segmentation in the fly embryo, mutations in which may be embryonic lethal. Patched functions as the receptor for the Hedgehog protein and controls its spatial distribution, in part via endocytosis of bound Hedgehog protein, which is then targeted for lysosomal degradation.
Pillow case
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Fill one with door knobs or padlocks and you have yourself a nice weapon.
Pillow case meaning & definition 1 of Pillow case.
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1.) what one puts on the ugliest person they are about to fuck; 2.) used to cover the pillow and serve as a protective outer layer against intruding elements
Pillow case meaning & definition 2 of Pillow case.
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n.- One who has expired; corpse ; [dirt nap] enthusiast
Pillow case meaning & definition 3 of Pillow case.
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When one punches a female in the breast.
Pillow case meaning & definition 4 of Pillow case.
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To shoot a bird with nearly all of your shot so that its feathers fly everywhere, just as it would look if you shot a pillow.
Pillow case meaning & definition 5 of Pillow case.
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