Patched (Ptc) is a conserved 12-pass transmembrane protein receptor that plays an obligate negative regulatory role in the Hedgehog signaling pathway in insects and vertebrates. Patched is an essential gene in embryogenesis for proper segmentation in the fly embryo, mutations in which may be embryonic lethal. Patched functions as the receptor for the Hedgehog protein and controls its spatial distribution, in part via endocytosis of bound Hedgehog protein, which is then targeted for lysosomal degradation.
Choir boy
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Term used to completely embarrass and degrade someone.
Originally from the Schwartzeneggers movie End of days (1999), used massively in Arnolds prank calls on youtube.
Choir boy meaning & definition 1 of Choir boy.
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a different word for pussy,chicken
Choir boy meaning & definition 2 of Choir boy.
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A boy who sings in a choir. All of whom can be put in at least one of the following catagories, leaving having a good relationship with them hopeless for any choir girl
1)happily taken
2)player
3)gay
4)weird, socially awkward and/or grossChoir boy meaning & definition 3 of Choir boy.
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a term used by guys who are too afraid to sing in front of people. also used to make fun of a guy who has choir on his letter jacket even though he gets more ass then the other guys.
Choir boy meaning & definition 4 of Choir boy.
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