Patched (Ptc) is a conserved 12-pass transmembrane protein receptor that plays an obligate negative regulatory role in the Hedgehog signaling pathway in insects and vertebrates. Patched is an essential gene in embryogenesis for proper segmentation in the fly embryo, mutations in which may be embryonic lethal. Patched functions as the receptor for the Hedgehog protein and controls its spatial distribution, in part via endocytosis of bound Hedgehog protein, which is then targeted for lysosomal degradation.
Sod
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The meaning sodomite is a little old fashioned. More typically its used as a softer form of fool, idiot, or bastard.
Sod meaning & definition 1 of Sod.
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A piece of dirt and grass, usually found stuck to the bottom of shoes after running (Or walking) On a muddy field.
Short for Sodomy, meaning anal sex, which comes from the Sodomites of Sodom. This term, usually used in a derogatory manner, can be used to say fuck off, as in Sod off or it can be used as an adjective That sodding bastard
An idiot, a fool. Someone you dislike.
Sod meaning & definition 2 of Sod.
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fool, foolish, idiot
used by the english more than anything.
Sod meaning & definition 3 of Sod.
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Brithish slang term meaning bastard
Sod meaning & definition 4 of Sod.
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A girl (or guy) looking to sit on dicks
Sod meaning & definition 5 of Sod.
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Originally sod meant a [clump] of [dirt] or earth.
Now it is a soft [curse word].
Sod meaning & definition 6 of Sod.
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