Patched (Ptc) is a conserved 12-pass transmembrane protein receptor that plays an obligate negative regulatory role in the Hedgehog signaling pathway in insects and vertebrates. Patched is an essential gene in embryogenesis for proper segmentation in the fly embryo, mutations in which may be embryonic lethal. Patched functions as the receptor for the Hedgehog protein and controls its spatial distribution, in part via endocytosis of bound Hedgehog protein, which is then targeted for lysosomal degradation.
Romero
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The most nicest people there are.
Romero meaning & definition 1 of Romero.
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A sex move in which you insert your finger into someones anus while giving them anal sex.
Romero meaning & definition 2 of Romero.
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Person who feels as though Rosemary is so expensive that in order to get their moneys worth, they have to try every sample available, often multiple times.
Romero meaning & definition 3 of Romero.
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a male, who is in love with other males.
Romero meaning & definition 4 of Romero.
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A fag.. usually a old man that is a teacher and has no friends... and has never been laid
Romero meaning & definition 5 of Romero.
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[Romero] is a Mexican last name but also In some cases a first name. Romero is a very intelligent, dedicated man. once he finds someone he loves he will do anything to show it. He’s very athletic best at sports like baseball. He can have trouble showing emotion to others but tries to [break through] it. He’s very handsome,tall and has a great muscular body. And most [importantly] amazing in bed. All the girls wanna be with a guy like [romero]
Romero meaning & definition 6 of Romero.
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[Spanish] rosemary.
Romero meaning & definition 7 of Romero.