Patched (Ptc) is a conserved 12-pass transmembrane protein receptor that plays an obligate negative regulatory role in the Hedgehog signaling pathway in insects and vertebrates. Patched is an essential gene in embryogenesis for proper segmentation in the fly embryo, mutations in which may be embryonic lethal. Patched functions as the receptor for the Hedgehog protein and controls its spatial distribution, in part via endocytosis of bound Hedgehog protein, which is then targeted for lysosomal degradation.
Shredded
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means well defined muscles especially in the arms and abs
Shredded meaning & definition 1 of Shredded.
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to have acquired 6% body fat.
Shredded meaning & definition 2 of Shredded.
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A verb: to do something amazing or to beat someone really bad in anything.
Shredded meaning & definition 3 of Shredded.
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To totally dominate the scales in scateboarding/snowboarding radness.
Shredded meaning & definition 4 of Shredded.
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to be absurdly sore. total muscle melt down
Shredded meaning & definition 5 of Shredded.
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extreme state of intoxiction from marijuana use often noted by staggering vision(like the picture lags) numbness of legs and arms very pleasurable feelings and sometimes paranoia,[stoned],[blazed],[high]
Shredded meaning & definition 6 of Shredded.
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A word coined by a group of teens in the Seattle area. It quickly caught on and now hundreds, maybe thousands of teens in the Washington area are now using the word in a variety of ways.
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Something cool, to be envious of.
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To be [wasted], [trashed], [drunk]...
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To be [high] or [tripping], especially on hallucinogenic drugs.
Shredded meaning & definition 7 of Shredded.
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to be salted, or insulted
Shredded meaning & definition 8 of Shredded.
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Can be used in place of many words ... but mainly describes someone who is way too drunk.
Shredded meaning & definition 9 of Shredded.
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An expression used to convay feelings of depression, grogginess, and/or hung over.
Shredded meaning & definition 10 of Shredded.
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having strong, well-developed muscles that can be seen through the skin, and little body fat:
Shredded meaning & definition 11 of Shredded.
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Torn or cut into shreds.
Shredded meaning & definition 12 of Shredded.