Patched (Ptc) is a conserved 12-pass transmembrane protein receptor that plays an obligate negative regulatory role in the Hedgehog signaling pathway in insects and vertebrates. Patched is an essential gene in embryogenesis for proper segmentation in the fly embryo, mutations in which may be embryonic lethal. Patched functions as the receptor for the Hedgehog protein and controls its spatial distribution, in part via endocytosis of bound Hedgehog protein, which is then targeted for lysosomal degradation.
Yucky
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drunk and crazy
Yucky meaning & definition 1 of Yucky.
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Something that is found repulsive by an 8 year old
Yucky meaning & definition 2 of Yucky.
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The word [teeny bopper]s use when they want to say something is gross or nasty.
Yucky meaning & definition 3 of Yucky.
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To be really high;;
If you smokey sticky icky;;therefore the icky will get you yuckyYucky meaning & definition 4 of Yucky.
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Messy or disgusting.
Yucky meaning & definition 5 of Yucky.
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