Patched (Ptc) is a conserved 12-pass transmembrane protein receptor that plays an obligate negative regulatory role in the Hedgehog signaling pathway in insects and vertebrates. Patched is an essential gene in embryogenesis for proper segmentation in the fly embryo, mutations in which may be embryonic lethal. Patched functions as the receptor for the Hedgehog protein and controls its spatial distribution, in part via endocytosis of bound Hedgehog protein, which is then targeted for lysosomal degradation.
Strait
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When something is cool. Basically just an Adj.
Strait meaning & definition 1 of Strait.
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Old and rarely used word meaning narrow
or tight.Also could mean straight (right).
Strait meaning & definition 2 of Strait.
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something that you can say in public not referring to people but is gay.
Strait meaning & definition 3 of Strait.
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A narrow passage of water connecting two seas or two other large areas of water.
Strait meaning & definition 4 of Strait.
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