Patched (Ptc) is a conserved 12-pass transmembrane protein receptor that plays an obligate negative regulatory role in the Hedgehog signaling pathway in insects and vertebrates. Patched is an essential gene in embryogenesis for proper segmentation in the fly embryo, mutations in which may be embryonic lethal. Patched functions as the receptor for the Hedgehog protein and controls its spatial distribution, in part via endocytosis of bound Hedgehog protein, which is then targeted for lysosomal degradation.
Pillows
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Large female breasts.
Pillows meaning & definition 1 of Pillows.
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Plural of [pillow], any of a specialized type of [cushion] to be found on a [bed] used mainly to cradle and support the head while sleeping
Pillows meaning & definition 2 of Pillows.
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A wicked Japanese punk rock band.
Pillows meaning & definition 3 of Pillows.
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females booty
Pillows meaning & definition 4 of Pillows.
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a rectangular cloth bag filled with soft material, such as feathers or artificial materials, used for resting your head on in bed:
Pillows meaning & definition 5 of Pillows.
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