Patched (Ptc) is a conserved 12-pass transmembrane protein receptor that plays an obligate negative regulatory role in the Hedgehog signaling pathway in insects and vertebrates. Patched is an essential gene in embryogenesis for proper segmentation in the fly embryo, mutations in which may be embryonic lethal. Patched functions as the receptor for the Hedgehog protein and controls its spatial distribution, in part via endocytosis of bound Hedgehog protein, which is then targeted for lysosomal degradation.
Slub
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A Man who no longer talks to his friends after he gets married.
Slub meaning & definition 1 of Slub.
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A combination of [slut] and [slob]: someone whose casual attitude toward sex mirrors their casual attitude toward fashion and hygiene.
Slub meaning & definition 2 of Slub.
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A slimy or revolting body appendage. ie. oily fingers, dirty toes
Slub meaning & definition 3 of Slub.
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Slub is the word to a girl who is slutty and chubby.
Slubby is the adjective form of the word slub.Slub meaning & definition 4 of Slub.
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Dislocating a dildo from your moms pussy while shes sleeping because youre too lazy to go to the store
Slub meaning & definition 5 of Slub.
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To club with a firm, yet slightly flexible object.
Mythical dolphin featured in the ancient art of [tae kwon dolphin].
Slub meaning & definition 6 of Slub.
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a word describing one who would be considered a slut in most situations but is to cool and has such a great personality that they are still respected by their peers and exempt from the word slut, whore, skank, ect.
Slub meaning & definition 7 of Slub.
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[a fat] [lazy] [fagot]
Slub meaning & definition 8 of Slub.
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[Slutty bitch], [pertaining] to two works slut and bitch conjugated together to create a single street word, slub. [Slubs] is the plural form of slub.
Slub meaning & definition 9 of Slub.