Patched (Ptc) is a conserved 12-pass transmembrane protein receptor that plays an obligate negative regulatory role in the Hedgehog signaling pathway in insects and vertebrates. Patched is an essential gene in embryogenesis for proper segmentation in the fly embryo, mutations in which may be embryonic lethal. Patched functions as the receptor for the Hedgehog protein and controls its spatial distribution, in part via endocytosis of bound Hedgehog protein, which is then targeted for lysosomal degradation.
Waitress
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A female waiter or attendant; a waiting maid or waiting
woman.
Waitress meaning & definition 1 of Waitress.
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a person who isnt [paid] enough to kiss the ass of some bastard who has had a [bad day] at the office and needs to [take it out] on someone.
Waitress meaning & definition 2 of Waitress.
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A woman most likely to [fart on] [your cake] if you abuse her or dont [tip] her well.
Waitress meaning & definition 3 of Waitress.
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Someone who would [fart] in your food (or possibly piss or [spit]) if you dont [treat] them right.
Waitress meaning & definition 4 of Waitress.
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Someone who brings food to a fat bastard who is [perving] on her and then gets [tipped] but only if she sleeps with the [customer]
Waitress meaning & definition 5 of Waitress.
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