Patched (Ptc) is a conserved 12-pass transmembrane protein receptor that plays an obligate negative regulatory role in the Hedgehog signaling pathway in insects and vertebrates. Patched is an essential gene in embryogenesis for proper segmentation in the fly embryo, mutations in which may be embryonic lethal. Patched functions as the receptor for the Hedgehog protein and controls its spatial distribution, in part via endocytosis of bound Hedgehog protein, which is then targeted for lysosomal degradation.
Realm
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A royal jurisdiction or domain; a region which is under the
dominion of a king; a kingdom.
Realm meaning & definition 1 of Realm.
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A spiritual state of mind
An astral plane where piece of mind and well-being are vital
realm- referring to an unearthly surrounding being positive or negative.Realm meaning & definition 2 of Realm.
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another dimension or universe,could possibly mean another life
Realm meaning & definition 3 of Realm.
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A realm is a human being thats existence in life is to be pointless, annoying and simple. There is often a realm in every friendship group whos sole purpose is to amuse there fellow human beings by being so silly. To describe a group of them, the word realmites is extremely appropriate.
Realm meaning & definition 4 of Realm.
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Realm integrates basic record keeping into the daily motion of church life to keep your staff equipped and your church body engaged. A software product by ACS Technologies
Realm meaning & definition 5 of Realm.