Patched (Ptc) is a conserved 12-pass transmembrane protein receptor that plays an obligate negative regulatory role in the Hedgehog signaling pathway in insects and vertebrates. Patched is an essential gene in embryogenesis for proper segmentation in the fly embryo, mutations in which may be embryonic lethal. Patched functions as the receptor for the Hedgehog protein and controls its spatial distribution, in part via endocytosis of bound Hedgehog protein, which is then targeted for lysosomal degradation.
Israelite
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A descendant of Israel, or Jacob; a Hebrew; a Jew.
Israelite meaning & definition 1 of Israelite.
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According to Deuteronomy 28, blacks, Hispanics and native American people are the Israelites the Bible speaks of.
Israelite meaning & definition 2 of Israelite.
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A member of the ancient Hebrew nation, especially in the period from the Exodus to the Babylonian Captivity (c.12th to 6th centuries BC).
Israelite meaning & definition 3 of Israelite.
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An old-fashioned and sometimes offensive term for a Jew.
Israelite meaning & definition 4 of Israelite.
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Relating to the Israelites.
Israelite meaning & definition 5 of Israelite.
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one of a race of people who lived in Israel in ancient times
Israelite meaning & definition 6 of Israelite.
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