Patched (Ptc) is a conserved 12-pass transmembrane protein receptor that plays an obligate negative regulatory role in the Hedgehog signaling pathway in insects and vertebrates. Patched is an essential gene in embryogenesis for proper segmentation in the fly embryo, mutations in which may be embryonic lethal. Patched functions as the receptor for the Hedgehog protein and controls its spatial distribution, in part via endocytosis of bound Hedgehog protein, which is then targeted for lysosomal degradation.
Different strokes for different folks
-
An expression meaning that everyone has their own way of doing things or approaching life. Often said in disagreement with how someone else has done things, but can also be said in a neutral or even positive fashion.
Different strokes for different folks meaning & definition 1 of Different strokes for different folks.
-
everyone has their own outlook on life
Different strokes for different folks meaning & definition 2 of Different strokes for different folks.
-
Refers to the fact that not all people like to get fucked the same way
Different strokes for different folks meaning & definition 3 of Different strokes for different folks.
Similar Words
What is Define Dictionary Meaning?
Define Dictionary Meaning is an easy to use platform where anyone can create and share short informal definition of any word.
Best thing is, its free and you can even contribute without creating an account.
This page shows you usage and meanings of Different strokes for different folks around the world.
Best thing is, its free and you can even contribute without creating an account.
This page shows you usage and meanings of Different strokes for different folks around the world.