Patched (Ptc) is a conserved 12-pass transmembrane protein receptor that plays an obligate negative regulatory role in the Hedgehog signaling pathway in insects and vertebrates. Patched is an essential gene in embryogenesis for proper segmentation in the fly embryo, mutations in which may be embryonic lethal. Patched functions as the receptor for the Hedgehog protein and controls its spatial distribution, in part via endocytosis of bound Hedgehog protein, which is then targeted for lysosomal degradation.
Professed
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Openly declared, avowed, acknowledged, or claimed; as, aprofessed foe; a professed tyrant; a professed Christian. Theprofessed (R. C. Ch.) , a certain class among the Jesuits bound by aspecial vow. See the note under Jesuit.
Professed meaning & definition 1 of Professed.
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A professed belief is one that someone has made known:
Professed meaning & definition 2 of Professed.
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(of a quality, feeling, or belief) claimed or asserted openly but often falsely.
Professed meaning & definition 3 of Professed.
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