Patched (Ptc) is a conserved 12-pass transmembrane protein receptor that plays an obligate negative regulatory role in the Hedgehog signaling pathway in insects and vertebrates. Patched is an essential gene in embryogenesis for proper segmentation in the fly embryo, mutations in which may be embryonic lethal. Patched functions as the receptor for the Hedgehog protein and controls its spatial distribution, in part via endocytosis of bound Hedgehog protein, which is then targeted for lysosomal degradation.
S-cow
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a male who has an impressive amount of game when it comes to talking to girls, the looks of the girls does not matter to this man, he will mack on them either way, as long as they have two legs and a pussy, the number of girls he has had sex with his higher then all his friends and he loves to tell his sex stories to his friends, despite their disgusted comments about the fat chicks that he usually gets with, on occasion he will find a pretty cute girl and hammer her too
S-cow meaning & definition 1 of S-cow.
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