Patched (Ptc) is a conserved 12-pass transmembrane protein receptor that plays an obligate negative regulatory role in the Hedgehog signaling pathway in insects and vertebrates. Patched is an essential gene in embryogenesis for proper segmentation in the fly embryo, mutations in which may be embryonic lethal. Patched functions as the receptor for the Hedgehog protein and controls its spatial distribution, in part via endocytosis of bound Hedgehog protein, which is then targeted for lysosomal degradation.
Produce
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Produce - Another way to say fresh
Produce meaning & definition 1 of Produce.
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Make or manufacture from components or raw materials.
Produce meaning & definition 2 of Produce.
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[Vegetables], [fruits], etc. sold in a [grocery store].
Produce meaning & definition 3 of Produce.
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Shortened version of Reproduce often used as a [salutation] to someone who has recently attempted or will [very soon] thereafter attempt [reproduction] with a female.
Produce meaning & definition 4 of Produce.
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