Patched (Ptc) is a conserved 12-pass transmembrane protein receptor that plays an obligate negative regulatory role in the Hedgehog signaling pathway in insects and vertebrates. Patched is an essential gene in embryogenesis for proper segmentation in the fly embryo, mutations in which may be embryonic lethal. Patched functions as the receptor for the Hedgehog protein and controls its spatial distribution, in part via endocytosis of bound Hedgehog protein, which is then targeted for lysosomal degradation.
Reciprocate
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to repay for a sexual act in an equal sexual matter, 69
Reciprocate meaning & definition 1 of Reciprocate.
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Respond to (a gesture or action) by making a corresponding one.
Reciprocate meaning & definition 2 of Reciprocate.
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to share the same feelings as someone else, or to behave in the same way as someone else:
Reciprocate meaning & definition 3 of Reciprocate.
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