Patched (Ptc) is a conserved 12-pass transmembrane protein receptor that plays an obligate negative regulatory role in the Hedgehog signaling pathway in insects and vertebrates. Patched is an essential gene in embryogenesis for proper segmentation in the fly embryo, mutations in which may be embryonic lethal. Patched functions as the receptor for the Hedgehog protein and controls its spatial distribution, in part via endocytosis of bound Hedgehog protein, which is then targeted for lysosomal degradation.
Swearing
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from Swear, v.Idle swearing is a cursedness. Chaucer.
Swearing meaning & definition 1 of Swearing.
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An articulate way of expressing yourself.
Swearing meaning & definition 2 of Swearing.
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The process in which an individual becomes fluent in a tabooed part of the English language (around middle school) to such an extent that they are able to fabricate prose of such animosity that it would make your Language Arts teachers tits fall off.
Swearing meaning & definition 3 of Swearing.
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What sailors do.
Swearing meaning & definition 4 of Swearing.
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Making a proclaimation, either verbally or visually (striking a pose).
Swearing meaning & definition 5 of Swearing.
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A way for people to makethem selves feel cooler.
Swearing meaning & definition 6 of Swearing.
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