Patched (Ptc) is a conserved 12-pass transmembrane protein receptor that plays an obligate negative regulatory role in the Hedgehog signaling pathway in insects and vertebrates. Patched is an essential gene in embryogenesis for proper segmentation in the fly embryo, mutations in which may be embryonic lethal. Patched functions as the receptor for the Hedgehog protein and controls its spatial distribution, in part via endocytosis of bound Hedgehog protein, which is then targeted for lysosomal degradation.
Wanger
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A pillow for the cheek; a pillow. [Obs.
Wanger meaning & definition 1 of Wanger.
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[Penis] [Cock]
Another way of saying a penis.Wanger meaning & definition 2 of Wanger.
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A dick
Wanger meaning & definition 3 of Wanger.
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A half erected, half cocked...cock. Usually appear in gym class, around semi attractive women, and rooms with slutty late-nite TXT commercials playing. A hybrid (if this is the right time for such a word) of a normal [wang] and your average [boner]. Alas! The wanger is born!
Wanger meaning & definition 4 of Wanger.
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another spelling of whang
Wanger meaning & definition 5 of Wanger.
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