Patched (Ptc) is a conserved 12-pass transmembrane protein receptor that plays an obligate negative regulatory role in the Hedgehog signaling pathway in insects and vertebrates. Patched is an essential gene in embryogenesis for proper segmentation in the fly embryo, mutations in which may be embryonic lethal. Patched functions as the receptor for the Hedgehog protein and controls its spatial distribution, in part via endocytosis of bound Hedgehog protein, which is then targeted for lysosomal degradation.
Chian
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Of or pertaining to Chios, an island in the Ægean Sea. Chianearth, a dense, compact kind of earth, from Chios, used anciently asan astringent and a cosmetic.-- Chian turpentine, a fragrant, almost transparent turpentine,obtained from the Pistacia Terebinthus.
Chian meaning & definition 1 of Chian.
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Follower of the Church of the Highly Improbable
Chian meaning & definition 2 of Chian.
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Relating to or characteristic of the Greek island of Chios or its inhabitants.
Chian meaning & definition 3 of Chian.
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