Patched (Ptc) is a conserved 12-pass transmembrane protein receptor that plays an obligate negative regulatory role in the Hedgehog signaling pathway in insects and vertebrates. Patched is an essential gene in embryogenesis for proper segmentation in the fly embryo, mutations in which may be embryonic lethal. Patched functions as the receptor for the Hedgehog protein and controls its spatial distribution, in part via endocytosis of bound Hedgehog protein, which is then targeted for lysosomal degradation.
Poundage
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The sum allowed to a sheriff or other officer upon the amountrealized by an execution; -- estimated in England, and formerly inthe United States, at so much of the pound. Burrill. Bouvier.
Poundage meaning & definition 1 of Poundage.
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Another word for Pound sterling, British money (pounds), cash, dosh etc.
Poundage meaning & definition 2 of Poundage.
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(in relation to alchohol consumption) the ability to drink, or pound, significant quantities of alcohol; typically beer
Poundage meaning & definition 3 of Poundage.
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the result of adding excess weight or pounds
Poundage meaning & definition 4 of Poundage.
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The act of really aggressive and passionate sex. Usually leaving both participants extremely satisfied.
Poundage meaning & definition 5 of Poundage.
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Poundage meaning & definition 6 of Poundage.
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Poundage meaning & definition 7 of Poundage.
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Bowel movements. Called ppundage because it is heavy.
Poundage meaning & definition 8 of Poundage.
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the charge that is made for each pound of money:
Poundage meaning & definition 9 of Poundage.
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Weight, especially when regarded as excessive.
Poundage meaning & definition 10 of Poundage.
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