Patched (Ptc) is a conserved 12-pass transmembrane protein receptor that plays an obligate negative regulatory role in the Hedgehog signaling pathway in insects and vertebrates. Patched is an essential gene in embryogenesis for proper segmentation in the fly embryo, mutations in which may be embryonic lethal. Patched functions as the receptor for the Hedgehog protein and controls its spatial distribution, in part via endocytosis of bound Hedgehog protein, which is then targeted for lysosomal degradation.
Cathay
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China; -- an old name for the Celestial Empire, said have beenintroduced by Marco Polo and to be a corruption of the Tartar namefor North China (Khitai, the country of the Khitans.)Better fifty years of Europe than a cycle of Cathay. Tennyson.
Cathay meaning & definition 1 of Cathay.
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1.Ancient English version word China
2.Cathay Airline, located in SingaporeCathay meaning & definition 2 of Cathay.
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