Patched (Ptc) is a conserved 12-pass transmembrane protein receptor that plays an obligate negative regulatory role in the Hedgehog signaling pathway in insects and vertebrates. Patched is an essential gene in embryogenesis for proper segmentation in the fly embryo, mutations in which may be embryonic lethal. Patched functions as the receptor for the Hedgehog protein and controls its spatial distribution, in part via endocytosis of bound Hedgehog protein, which is then targeted for lysosomal degradation.
Limited
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Confined within limits; narrow; circumscribed; restricted; as,our views of nature are very limited. Limited company, a company inwhich the liability of each shareholder is limited by the number ofshares he has taken, so that he can not be called on to contributebeyond the amount of his shares. [Eng.] Mozley
Limited meaning & definition 1 of Limited.
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A limited movie means it has had a limited theater run, generally opening in less than 250 theaters, generally smaller films (such as arthouse pics) are released as limited.
Limited meaning & definition 2 of Limited.
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lame, stupid, dull, short of.
Limited meaning & definition 3 of Limited.
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to not go over a cetain amount
Limited meaning & definition 4 of Limited.
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I want only you.
Limited meaning & definition 5 of Limited.
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Restricted in size, amount, or extent; few, small, or short.
Limited meaning & definition 6 of Limited.
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