Patched (Ptc) is a conserved 12-pass transmembrane protein receptor that plays an obligate negative regulatory role in the Hedgehog signaling pathway in insects and vertebrates. Patched is an essential gene in embryogenesis for proper segmentation in the fly embryo, mutations in which may be embryonic lethal. Patched functions as the receptor for the Hedgehog protein and controls its spatial distribution, in part via endocytosis of bound Hedgehog protein, which is then targeted for lysosomal degradation.
Panromantic demisexual
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A [panromantic] [demisexual] is a person who is attracted to any gender (whether it be [transgender],[straight] etc), but they will have to establish a deep friendship before they feel any attraction towards the other person.
Panromantic demisexual meaning & definition 1 of Panromantic demisexual.
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A [panromantic] [demisexual] is a person who is attracted to any gender (whether it be [transgender],[straight] etc), but they will have to establish a deep friendship before they feel any attraction towards the other person.
Panromantic demisexual meaning & definition 2 of Panromantic demisexual.
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A panromantic Demisexual is someone who is romantically attracted to anyone of any orientation, but not be sexually attracted to them, unless they have a strong bond with them.
Panromantic demisexual meaning & definition 3 of Panromantic demisexual.
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The meaning of Panromantic Demisexual is someone who is romantically attracted to everyone, regardless of gender or sexuality. But they cannot be sexually attracted to someone unless they form a strong bond or friendship first.
Panromantic demisexual meaning & definition 4 of Panromantic demisexual.
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The meaning of Panromantic Demisexual is someone who is romantically attracted to everyone, regardless of gender or sexuality. But they cannot be sexually attracted to someone unless they form a strong bond or friendship first.
Panromantic demisexual meaning & definition 5 of Panromantic demisexual.