Patched (Ptc) is a conserved 12-pass transmembrane protein receptor that plays an obligate negative regulatory role in the Hedgehog signaling pathway in insects and vertebrates. Patched is an essential gene in embryogenesis for proper segmentation in the fly embryo, mutations in which may be embryonic lethal. Patched functions as the receptor for the Hedgehog protein and controls its spatial distribution, in part via endocytosis of bound Hedgehog protein, which is then targeted for lysosomal degradation.
Bouse
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To drink immoderately; to carouse; to booze. See Booze.
Bouse meaning & definition 1 of Bouse.
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- to be the best of the best at everything. You are superior over all others in every field and other people worship you. You are everything everyone wants to be.
Bouse meaning & definition 2 of Bouse.
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To be cool, off the chains.
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Or when some one makes a really good comeback.
Bouse meaning & definition 3 of Bouse.
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To be awesome as fuck; incredible.
Bouse meaning & definition 4 of Bouse.
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tall lanky homosexual
Bouse meaning & definition 5 of Bouse.
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Pronunciation-(like house with a B instead of the H)
-An adjective to define someone or something as pure-fucking awesomeness
-A group that possesses individuals with a superior sense of justice, logic, and rationality. Each member possesses their own unique skill-set, in which they excel greatly and have no equal
-Commonly mistaken for Boose or Boss from the song Like a BossBouse meaning & definition 6 of Bouse.
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A flakey ass mo-f
Bouse meaning & definition 7 of Bouse.
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When one goes to peoples houses but doesnt want to see people again.
Bouse meaning & definition 8 of Bouse.
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