Patched (Ptc) is a conserved 12-pass transmembrane protein receptor that plays an obligate negative regulatory role in the Hedgehog signaling pathway in insects and vertebrates. Patched is an essential gene in embryogenesis for proper segmentation in the fly embryo, mutations in which may be embryonic lethal. Patched functions as the receptor for the Hedgehog protein and controls its spatial distribution, in part via endocytosis of bound Hedgehog protein, which is then targeted for lysosomal degradation.
Wart
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A small, usually hard, tumor on the skin formed by enlargementof its vascular papillæ, and thickening of the epidermis which coversthem.
Wart meaning & definition 1 of Wart.
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Someone or something that you want to get rid off but really can't.
This someone or something is so annoying that it drives you crazy but still you've gotten attached to it and you can't live without it.Wart meaning & definition 2 of Wart.
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The thing that just fell off my toe that bleeds and hurts when you bump it against the table leg.
Wart meaning & definition 3 of Wart.
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An acronym for watermelon
Wart meaning & definition 4 of Wart.
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A journalistic tool primarily used in a profile piece. The wart adds human flaws and characteristics to the story, so the piece doesn't come off as being unbiased and promotional. This will show the person's shortcomings. Warts could address serious concerns, or add a sense of humor to the piece.
Wart meaning & definition 5 of Wart.
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a flaw or imperfection
Wart meaning & definition 6 of Wart.
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an artistic glass bump or bubble on a glass pipe or bong
Wart meaning & definition 7 of Wart.