Patched (Ptc) is a conserved 12-pass transmembrane protein receptor that plays an obligate negative regulatory role in the Hedgehog signaling pathway in insects and vertebrates. Patched is an essential gene in embryogenesis for proper segmentation in the fly embryo, mutations in which may be embryonic lethal. Patched functions as the receptor for the Hedgehog protein and controls its spatial distribution, in part via endocytosis of bound Hedgehog protein, which is then targeted for lysosomal degradation.
Dumple
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To make dumpy; to fold, or bend, as one part over another. [R.]He was a little man, dumpled up together. Sir W. Scott.
Dumple meaning & definition 1 of Dumple.
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a mascot that might have been dumplings but the creators were really hungry and tired and all they could come up with Dumples.
Dumple meaning & definition 2 of Dumple.
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Official mascot of CGNU.
Dumple meaning & definition 3 of Dumple.
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A [telnet] [BBS] Server written in [Python] scripting language.
Dumple was developed by Titans of Old in 2003. It allows old DOS based BBS software and doors to be accessed from a web browser. Dumple is open source freeware.Dumple meaning & definition 4 of Dumple.
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n. Small pile of excretement. A term used exclusively by small children and rich urbanites with tiny dogs.
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Dumple meaning & definition 5 of Dumple.
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n. Cute dimple visible on the top of a fresh pile of dog feces.
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Dumple meaning & definition 6 of Dumple.
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A word you get when you are like tryn to make up a mascot name and youre frickin hungry!
Dumple meaning & definition 7 of Dumple.
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verb.
to buy dumplings from a cheap restaurant that offers delivery, esp. at 2am while working on psets.Dumple meaning & definition 8 of Dumple.
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A noun or [pet name] predominately used by a [spouse] to describe thier affection towards thier partner.
Dumple derives from the word dumpling. Its meaning is tasty and cute like a [dumpling]... but bigger.
Dumple meaning & definition 9 of Dumple.