Patched (Ptc) is a conserved 12-pass transmembrane protein receptor that plays an obligate negative regulatory role in the Hedgehog signaling pathway in insects and vertebrates. Patched is an essential gene in embryogenesis for proper segmentation in the fly embryo, mutations in which may be embryonic lethal. Patched functions as the receptor for the Hedgehog protein and controls its spatial distribution, in part via endocytosis of bound Hedgehog protein, which is then targeted for lysosomal degradation.
Barbarian
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Of, or pertaining to, or resembling, barbarians; rude;uncivilized; barbarous; as, barbarian governments or nations.
Barbarian meaning & definition 1 of Barbarian.
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The superior race. Barbarians are large and muscular and are very good at most tasks. Barbarians are either really nice guys and help out anyone who needs help, or really malevolent who kill whole towns and eat their victims
Barbarian meaning & definition 2 of Barbarian.
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A librarian that cuts hair.
As said in the Disney cartoon Dave the Barbarian.Barbarian meaning & definition 3 of Barbarian.
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Big guys who brandishes shiny sturdy weapons and commits mass murder without remorse. Loves meat and women, hates books and intellectuals, especially magic-users. Live fast and die happy...
Also a fighter unparalled in close-combat in [Diablo 2], a hack and slash plus sorcery game.Barbarian meaning & definition 4 of Barbarian.
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The large and burly race who live in Halas or Harrogath and wield massive weapons and kill everyone and eat their victim's BONES!
Barbarian meaning & definition 5 of Barbarian.
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When a guy violently masturbates beats his cock while screaming, RAHAHAHAHA!!!!.
Barbarian meaning & definition 6 of Barbarian.
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Weed that is very potent that one hit would fucked you up in a sec and bring you down for hours only true stoners have every held this type of weed its mostly the haze type especially the Barbarian Piff
Barbarian meaning & definition 7 of Barbarian.
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A certain class of gent who actually prefers the ‘bloody axe wound’ during ‘that time of the month’.
Barbarian meaning & definition 8 of Barbarian.
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Also known as [Beserkers], the Barbarian is a Warrior who uses brute force as a weapon. The Barbarian is by no means at all very intelligent, but it is extremely skilled at killing nonetheless. The Barbarian is best known for his battle rages. As the battle rages on, the Barbarian can let out an earth-shaking roar that allows him to access the hidden strangth within him. Thus, the Barbarian is even more ruthless and more powerful. One interesting thing to note is that no Barbarian has ever surrendered.
Barbarian meaning & definition 9 of Barbarian.