Patched (Ptc) is a conserved 12-pass transmembrane protein receptor that plays an obligate negative regulatory role in the Hedgehog signaling pathway in insects and vertebrates. Patched is an essential gene in embryogenesis for proper segmentation in the fly embryo, mutations in which may be embryonic lethal. Patched functions as the receptor for the Hedgehog protein and controls its spatial distribution, in part via endocytosis of bound Hedgehog protein, which is then targeted for lysosomal degradation.
Breakaway
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A wild rush of sheep, cattle, horses, or camels (especially atthe smell or the sight of water); a stampede.
Breakaway meaning & definition 1 of Breakaway.
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song by Kelly Clarkson that is one of her best ever! love it!
Breakaway meaning & definition 2 of Breakaway.
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an act of separating from a group, especially because of disagreement:
Breakaway meaning & definition 3 of Breakaway.
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A divergence or radical change from something established or long standing.
Breakaway meaning & definition 4 of Breakaway.
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